大家网记者 金冠超 通信员 李成强 潍坊报谈
r肖先生是一位67岁的男性患者,岁首因腹胀行腹部强化CT及B超搜检,均教导填塞性肝占位。接洽患者AFP升高彰着及肝炎、肝硬化病史,临床会诊为肝细胞癌并多发肝鼎新。随后依据诊疗指南赐与“贝伐珠单抗+信迪利单抗”决议颐养2周期,复查肝脏肿瘤较前松开。接续赐与2周期颐养,患者出现病情推崇,之后赐与阿帕替尼口服颐养1周期,评价再次出现推崇,更换为仑伐替尼靶向颐养1周期,病情仍出现推崇。
r主治大夫随之提议行化疗颐养,但家属有计划患者体魄弱,牵记不良反映,辩认化疗,使颐养一时堕入僵局,家属也作念了最坏的蓄意。
r此时,恰逢科室副主任孙锦贵熟习肿瘤介入颐养时候回归。主任李广连在抽象有计划患者各方面要素后,向患者家属提议行HAIC颐养,同期赐与小范围介入栓塞颐养。经过长远浅出地教化具体操作经过、预期成果及可能出现的不良反映,家属终末听取了李主任的提议。
r为全力作念好患者置管后的颐养职责,顾问长王海玲携带总计看护团队对肝动脉插管及防卫化疗进行了全面、系统地学习,实在作念到了对术前、术后健康教育、防卫药物的浓度及滴速条款、药物防卫经过可能出现的风险及处分方法等的谙熟于心,切实消灭了患者黄雀伺蝉。
rrr总计手术仅执续了十几分钟,便顺利完成。复返病房后,执续36h的防卫化疗,患者渺小纳差、乏力,耐受细致,术后5天顺利出院。间隔3周返院复查,患者自愬体魄状况较前彰着好转,复查CT教导肿瘤较前彰着松开,现患者已积极准备,择期行第2次HAIC颐养。
rr拓展阅读
r什么是HAIC
rHAIC即肝动脉防卫化疗,是在数字减影血管造影(DSA)的教悔下,经股动脉插管至肝肿瘤供血动脉内并保留导管,将化疗药执续注入肿瘤供血动脉的一种区域性局部化疗,是微创介入的一种花式。HAIC现已成为中晚期肝癌的进军颐养才智,被写入国度卫健委《原发性肝癌诊疗指南(2022版)》中。
rHAIC颐养的上风
r化疗不良反映轻:当药物经过肝脏的时候,70%-95%的比例被首过摈斥,闯过肝脏干涉体轮回中的药物剂量较低,比拟全身颐养显贵缩小了毒副反映。
r局部药物浓度高:成例静脉化疗,仅有5%傍边的药物到达肝脏,作用于肿瘤;比拟之下,HAIC摄取肝脏肿瘤动脉置管执续给药花式,径直将高浓度的化疗药物防卫至肿瘤供血动脉,局部药物浓度显贵擢升,延迟化疗药物的作用时辰。
rHAIC颐养得当东谈主群
rTACE颐养后复发的肝癌患者;晚期弗成切除的肝癌患者;填塞型或归并门静脉瘤栓的肝癌患者;弗成切除的肝鼎新瘤患者。
rHAIC的颐养疗程
rHAIC颐养灵验的情况下,提议HAIC颐养督察4—6个疗程;肝癌HAIC颐养成例每3周类似1次,提议每2—3次HAIC后复查影像学进行疗效评估。
","del":0,"gnid":"91c7519d888d99056","img_data":[{"flag":"2","img":[{"desc":"","height":"396","title":"","url":"http://p9.img.360kuai.com/t11508c75c81ec2e6b47fcc75c9.jpg","width":"550"},{"desc":"","height":"412","title":"","url":"http://p9.img.360kuai.com/t11508c75c876753dbffd57cd48.jpg","width":"550"},{"desc":"","height":"193","title":"","url":"http://p9.img.360kuai.com/t11508c75c8a9d96345eee3b9d0.jpg","width":"550"}]}],"original":0,"pat":"art_src_1,fts0,sts0","powerby":"pika","pub_time":1717585358000,"pure":"","rawurl":"http://zm.news.so.com/be5dc1fe422faca559c0c738678cabb2","redirect":0,"rptid":"c1e150b13e609ff4","rss_ext":[],"s":"t","src":"大家网","tag":[{"clk":"khealth_1:肝癌患者","k":"肝癌患者","u":""},{"clk":"khealth_1:肿瘤","k":"肿瘤","u":""},{"clk":"khealth_1:肝脏","k":"肝脏","u":""},{"clk":"khealth_1:肝癌","k":"肝癌","u":""}],"title":"涸鱼得水丨寿光抽象病院HAIC颐养为肝癌晚期患者带来新但愿","type":"zmt","wapurl":"http://zm.news.so.com/be5dc1fe422faca559c0c738678cabb2","ytag":"健康:健康行业资讯:病院","zmt":{"brand":{},"cert":"大家网官方账号","desc":"全省最大的新闻外宣派别网站坚执正确的公论导向濒临活命面向大家","fans_num":99660,"id":"1266166238","is_brand":"0","name":"大家网","new_verify":"4","pic":"https://p1.img.360kuai.com/t017318f73fb119cc6b.png","real":1,"textimg":"https://p9.img.360kuai.com/bl/0_3/t017c4d51e87f46986f.png","verify":"0"},"zmt_status":0}","errmsg":"","errno":0}